Depression and nitric oxide: Feeling low on low NO

by on November 15, 2011

Depressive disorders are quite common issues; doctors write about 2.30 million prescriptions for antidepressants year after year. NO can help those drugs work.

Antidepressants are pro-NO

In a research based on 70 people, people who were depressed had “considerably lesser” levels’ of NO compared to those who weren’t, claimed Japanese researchers. And any time the scientists treated the depressed people with an antidepressant, NO levels “substantially increased” in four weeks. “Decreased blood levels of NO might be partially associated with the pathophysiology [development] of depression,” according to the researchers in the journal Progress in Neuro,Psychopharmacology and Biological Psychiatry.

In a very much same study on researchers in the Department of Psychiatry at the University of Alberta in Canada, blood levels of NO were “considerably lower” in individuals with depression in comparison to those who weren’t depressed, and therapy with an antidepressant increased NO levels.

Memory Loss: Don’t Forget NO!

Can’t remember where you put your keys? You may have lost your NO, too.”There is a remarkable proof recommending the involvement of NO in … learning and memory,” wrote a team of Iranian researchers in the journal Behavioural Brain Research.

NO is essential for good memory

In their animal study, they discovered that blocking the production of NO hurt both short, and long. term memory, and that giving the animals NO increasing LĀ·arginine countered memory difficulties. An animal study by Israeli researchers, in the Journal of Neuroscience, indicated that NO is essential for fotihing short-term, interrmediate term, and long, term memories. And in one more animal study, Argentine scientists learned that NO becomes necessary for the storage and retrieval of memory. Their conclusions were in the journal Neurobiology of Learning and Memory.

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